What are the risk factors and causes of bipolar disorder?

Key points
- Genetic or hereditary factors contribute to the risk of bipolar disorder.
- Studies of identical twins suggest that both genes and other factors play a role in the cause of bipolar disorder.
- However, if one twin has bipolar disorder, the other twin is more likely to develop the illness.
- Other than genetic factors, there are no other known risk factors for bipolar disorder.
Genetic or hereditary factors contribute to the risk of bipolar disorder. Studies have demonstrated that the prevalence of bipolar disorder is higher among the parents of bipolar patients. However, hereditary factors are not the only cause of bipolar disorder.
Studies of identical twins suggest that both genes and other factors play a role in the cause of bipolar disorder. Identical twins share all the same genes. If bipolar disorder were caused entirely by genes, then the identical twin of a patient with the illness would always develop the illness, which is not the case.
However, if one twin has bipolar disorder, the other twin is more likely to develop the illness. There is a slightly greater risk of developing the disease among siblings as well.
Other than genetic factors, there are no other known risk factors for bipolar disorder. Lack of sleep may predispose individual patients to a recurrence of symptoms. Psychological and hormonal factors are suspected of playing a role as well. Some medications and illnesses cause symptoms that mimic bipolar disorder. It is important for these to be ruled out before a diagnosis of bipolar disorder is made.
Written and revised by
Andrey Nailor, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.
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