Possible Side Effects of EFFEXOR XR

Key points
- In clinical studies, few people had to stop taking EFFEXOR XR because of side effects.
- EFFEXOR XR may cause an increase in your cholesterol.
- Symptoms are known to occur when people stop using EFFEXOR XR, especially when they suddenly stop therapy.
- Your doctor may want to do blood tests to check your serum cholesterol periodically.
EFFEXOR XR may cause side effects in some people. In clinical studies, few people had to stop taking EFFEXOR XR because of side effects.
In clinical studies, the most common side effects included:
| NauseaDizzinessSleepinessAbnormal ejaculationSweatingDry mouthGasAbnormal vision | NervousnessInsomniaAnorexiaConstipationConfusion/agitationTremorYawningPalpitation |
Tell your doctor right away if you have
- increases in heart rate.
- extreme confusion or seizures, which may indicate very low levels of sodium in the blood.
- abnormal bleeding or bruising.
- sudden, unexpected eye pain, eye redness, or changes in vision, which may indicate increased eye pressure.
- symptoms of mania or hypomania, such as persistently elevated or irritable mood, a decreased need for sleep, racing thoughts, hyperactivity, and rapid, excessive speech.
EFFEXOR XR may cause an increase in your cholesterol. Your doctor may want to do blood tests to check your serum cholesterol periodically.
What happens when I stop using EFFEXOR XR?
Symptoms are known to occur when people stop using EFFEXOR XR, especially when they suddenly stop therapy.
When people suddenly stop using EFFEXOR XR, they can get symptoms from stopping the medicine too fast. Some of these symptoms include
| AgitationAnxietyConfusionDiarrheaDizziness or vertigoDry mouthFasciculation (muscle twitching)HeadachesHypomaniaImpaired coordinationInsomnia (trouble sleeping)Loss of appetite | NauseaNervousnessNightmaresSensory disturbances (including electric shock sensations)Somnolence (sleepiness)SweatingTinnitusTirednessTremorUnpleasant moodVomiting |
Do not stop taking EFFEXOR XR without talking with your doctor first. Your doctor may want to slowly decrease your dose of EFFEXOR XR to help avoid these kinds of symptoms.
Written and revised by
Andrey Nailor, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.
Explore health topics
More in this topic
Mental Health →
NewsWork Possible With Early Alzheimer's
About 200,000 Americans are estimated to have early-onset Alzheimer's disease, which means the disease is found before age 65. Alzheimer's is the most common form of dementia, and it a causes significant memory and…
26 August 2011
NewsUC Study Reveals Possible Brain Damage in Young Adult Binge-Drinkers
It’s considered a rite of passage among young people – acting out their independence through heavy, episodic drinking. But a new University of Cincinnati study, the first of its kind nationally, is showing how binge…
28 June 2011
NewsSuccessful depression treatment of mothers has long-term effects on offspring
Children whose mothers are successfully treated for depression show progressive and marked improvement in their own behaviors even a year after their moms discontinue treatment, new UT Southwestern Medical Center-led…





