Diagnosis and Management of Generalized Anxiety Disorder
Key points
- Several authors have suggested that patients be treated with the lowest effective dose and re-evaluated for medication discontinuance at 6-month intervals.
- Approximately 50% of patients successfully treated with either clorazepate or Buspirone will relapse upon drug discontinuation at 6 months.
- This indicates that about one-half of GAD patients can benefit from short-term treatment, while the rest require more prolonged therapy.
- However, patients treated with benzodiazepines have twice the recurrence of anxiety symptoms or need further antianxiety treatment than do those treated with nonbenzodiazepine medications.
Treatment Duration
The duration of treatment of GAD is uncertain. Several authors have suggested that patients be treated with the lowest effective dose and re-evaluated for medication discontinuance at 6-month intervals.
Approximately 50% of patients successfully treated with either clorazepate or Buspirone will relapse upon drug discontinuation at 6 months.
This indicates that about one-half of GAD patients can benefit from short-term treatment, while the rest require more prolonged therapy. However, patients treated with benzodiazepines have twice the recurrence of anxiety symptoms or need further antianxiety treatment than do those treated with nonbenzodiazepine medications. Some experts suggest that medications that do not produce euphoria and sedation, such as Buspirone or antidepressants, may allow the patient to make more progress in coping skills and anxiety-management behavior than with benzodiazepines.
Written and revised by
David Cohen, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.
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