Depression Twice as Likely in Seizure Sufferers

A new study published in Epilepsia finds that the prevalence of depression is almost twice as high in people with epilepsy compared to the general population. Among those with epilepsy, racial minorities have seven times the odds of depression in comparison to the majority Caucasian population. The findings also show that 40 percent of depressed respondents with epilepsy were not accessing mental healthcare services.

Data from the 2000 ⁄ 2001 Canadian Community Health Survey was used to determine prevalence of epilepsy and depression. 13 percent of those with epilepsy were found to suffer from depression, compared to 7 percent of those without the disorder. Epilepsy was also associated with 43 percent higher odds of depression when adjusting for demographic factors.

The odds were higher not only for minorities, but also for females, older adults and individuals experiencing food insecurity. Minority status and advanced age appear to be unique risk factors for depression in those with epilepsy, as these factors are not associated with depression in the general population.

Previous research indicates that, on average, individuals with epilepsy suffer from a greater number of chronic conditions, have worse self-reported health and experience increased pain. They are also more likely to have a lower quality-of-life, related to both health and other factors. Individuals with epilepsy have also been found to exhibit higher levels of recent psychological distress, a greater likelihood for a variety of psychiatric conditions and a higher prevalence of suicidal thoughts. Sufferers also typically have lower incomes, less education and are less likely to have full- or part-time employment.

“Individuals with epilepsy are vulnerable to depression , yet we have identified an important gap in mental health service provision,” says Esme Fuller-Thomson of the University of Toronto , co-author of the study. “Routine screening and targeted interventions for depression are needed to help serve those with epilepsy.”

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This study is published in Epilepsia. Media wishing to receive a PDF of this article may contact [email protected].

To view the abstract for this article, please click here.

Esme Fuller-Thomson is an associate professor at the University of Toronto and can be reached for questions at [email protected].

Epilepsia is the leading, most authoritative source for current clinical and research results on all aspects of epilepsy. As the journal of the International League Against Epilepsy, subscribers every month will review scientific evidence and clinical methodology in: clinical neurology, neurophysiology, molecular biology, neuroimaging, neurochemistry, neurosurgery, pharmacology, neuroepidemiology, and therapeutic trials. For more information, please visit www.blackwell-synergy.com/loi/epi.