Tolbutamide (Oral)
Key points
- You should not use this medicine if you have ever had an allergic reaction to tolbutamide or other sulfonylurea drugs such as Tolinasereg;, chlorpropamide, or Glucotrolreg;.
- Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- If you notice other side effects that you think are caused by this medicine, tell your doctor.
- You should not use this medicine if you are pregnant.
Tolbutamide (By Mouth)
Tolbutamide (tole-BYOO-ta-mide)
Treats diabetes mellitus (sugar diabetes). Belongs to a class of drugs called sulfonylureas.
Brand Name(s):
Tol-Tab
There may be other brand names for this medicine.
When This Medicine Should Not Be Used:
You should not use this medicine if you have ever had an allergic reaction to tolbutamide or other sulfonylurea drugs such as Tolinasereg;, chlorpropamide, or Glucotrolreg;. You should not use this medicine if you are pregnant.
How to Use This Medicine:
Tablet
- Your doctor will tell you how much to take and how often.
If a dose is missed:
- Take the missed dose as soon as possible.
- Skip the missed dose if it is almost time for your next regular dose.
- You should not use two doses at the same time.
How to Store and Dispose of This Medicine:
- Store at room temperature, away from heat, moisture, and direct light.
- Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Avoid drinking alcohol while you are taking this medicine.
- While using this medicine, avoid taking aspirin or cough and cold medicines.
- Tolbutamide interacts with many medicines. Before you start taking tolbutamide, make sure your doctor knows of all other medicines you are taking.
Warnings While Using This Medicine:
- Talk with your doctor before taking this medicine if you are breastfeeding or if you have liver, kidney, or heart disease, G-6-PD deficiency, or a thyroid disorder.
- To control your diabetes, follow the diet that your doctor orders and take this medicine on a regular schedule.
- You may have low blood sugar while you are taking tolbutamide, especially if you miss a meal, exercise for a long time, or drink alcohol. Symptoms of low blood sugar include sweating, feeling very hungry, fast heartbeat, drowsiness, confusion, headache that won't go away, chills, or vomiting.
Written and revised by
David Cohen, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.