Methotrexate (Oral)

Methotrexate (By Mouth)

Methotrexate (meth-oh-TREX-ate)

Treats several kinds of cancer, including cancer of the blood, bone, lung, breast, head, or neck. Also treats rheumatoid arthritis and psoriasis (a skin disease).

Brand Name(s):

Rheumatrex Dose Pack, Trexall
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to methotrexate or if you are breastfeeding. You should not use this medicine for arthritis or psoriasis if you are pregnant, or if you have liver disease or certain problems with your blood or immune system. Make sure your doctor knows if you drink alcohol of any kind on a regular basis.

How to Use This Medicine:

Tablet

• Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
  
• Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.The correct schedule for this medicine is different for arthritis, psoriasis, and different kinds of cancer. For example, people who have arthritis or psoriasis often take this medicine only once a week.
  
• Make sure you understand your personal dosing schedule. Ask your doctor and pharmacist if you are not sure when or how often to take your medicine.
  
• If you take the medicine only once a week, it is best to take it on the same day each week.
  
• Write down on a calendar or piece of paper when you are supposed to use your medicine. Keep the calendar or paper where you can see it. After you take your dose of medicine, cross off that date on your calendar or paper. This will help you remember if you took the medicine or if you still need to take it. If you need other ideas to help you keep track of your schedule, ask your pharmacist or other healthcare provider.
  

If a dose is missed:

• If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
  
• If you use this medicine only once a week and you miss a dose or forget to use your medicine, skip the missed dose and use your medicine as soon as possible. Return to your regular schedule the following week. Do not use extra medicine to make up for a missed dose.