Acupuncture Reduces Nausea and Vomiting, Pain After Major Breast Surgery

In the first such clinical trial of its kind, researchers at Duke University Medical Center have found that acupuncture is more effective at reducing nausea and vomiting after major breast surgery than the leading medication.

The researchers also found that patients who underwent the 5,000-year-old Chinese practice reported decreased postoperative pain and increased satisfaction with their postoperative recovery. In conducting the trial, the researchers also demonstrated that the pressure point they stimulated possesses previously unknown pain-killing properties.

Results of the Duke study were published Sept. 22, 2004, in the journal Anesthesia and Analgesia.

Treating postoperative nausea and vomiting (PONV) is an important medical issue. About 70 percent of women who undergo major breast surgery requiring general anesthesia suffer from this complication, according to Duke anesthesiologist Tong Joo (T.J.) Gan, M.D., who led the trial. These adverse side effects are important factors in determining how soon patients can return home after surgery.

"The patients in our randomized trial who received acupuncture enjoyed a more comfortable recovery from their surgery than those who received an antisickness medication," Gan said. "In the areas of PONV control, pain relief, and general overall satisfaction, acupuncture appears to be more effective than the most commonly used medication, with few to no side effects."

In the trial, Gan employed an electro-acupuncture device in which an electrode - like that used in standard EKG tests - is attached at the appropriate point. In this case, the point is known as P6 and is located below the wrist. Instead of actually breaking the skin with the traditional long slender needles, the electro-acupuncture device delivers a small electrical pulse through the skin.

"Electro-acupuncture enhances or heightens the effects of traditional acupuncture," Gan explained. "Also, in the busy and complicated setting of the operating room, the electro-acupuncture device is much more convenient to use."

The researchers enrolled 75 women who were to undergo major breast surgery (breast augmentation, breast reduction or mastectomy) requiring the use of general anesthesia. They were then randomized into three groups: one which received acupuncture, one which received the medication ondansetron (trade name Zofran), and a group that received neither.

The surgeries lasted anywhere from two to four hours, and the incidence of PONV and pain were tracked at 30-minute intervals for the first two hours after surgery, and then again 24 hours later.

Two hours after surgery, 77 percent of the patients receiving acupuncture experienced no PONV, nor did they require an antiemetic drug to reduce nausea and vomiting, compared to 64 percent for those who received ondansetron and 42 percent who received nothing. At 24 hours, the rates were 73 percent, 52 percent and 38 percent, respectively.