Cholesterol Lowering Medications

Key points
- To reach an LDL-cholesterol goal of less than 100 mg/dL, you may need to take a cholesterol-lowering medicine in addition to making the life habit changes already mentioned.
- If you have an LDL level of 130 mg/dL or greater, you will generally need to take an LDL-lowering medicine.
- Heart disease patients and those at high risk for developing heart disease need to lower their LDL more than other people.
- As a result, medications are more often used by patients with Heart disease and those at high risk than by those who do not have heart disease or who have a lower risk of developing it.
To reach an LDL-cholesterol goal of less than 100 mg/dL, you may need to take a cholesterol-lowering medicine in addition to making the life habit changes already mentioned. Heart disease patients and those at high risk for developing heart disease need to lower their LDL more than other people. As a result, medications are more often used by patients with Heart disease and those at high risk than by those who do not have heart disease or who have a lower risk of developing it.
Cholesterol-Lowering Medications and You
If you have an LDL level of 130 mg/dL or greater, you will generally need to take an LDL-lowering medicine. If your LDL level is 100 to 129 mg/dL, your doctor will consider all the facts of your case in deciding whether to prescribe medication for further LDL lowering or for high triglycerides and/or low HDL if they are present. If you have been hospitalized for a Heart Attack, your doctor will likely start you on a medication at discharge if your LDL-cholesterol is 130 mg/dL or greater. If your LDL-cholesterol is between 100 and 129 mg/dL during your hospitalization, your doctor may choose to start you on an LDL-lowering medication before you are discharged. Also, if your LDL-cholesterol is far above the goal level of less than 100 mg/dL when first measured, your doctor may choose to start a cholesterol-lowering medication together with diet and physical activity right from the beginning of treatment. If your doctor prescribes medicine, you also will need to:
If following a low-saturated-fat, low-cholesterol diet, increasing your physical activity, and losing weight have not lowered your risk for developing CHD after about 3 months, your doctor may consider prescribing a cholesterol-lowering medication. If your doctor prescribes medicine, you also will need to:
- Continue to follow your cholesterol-lowering diet
- Be more physically active
- Lose weight if overweight
- Control all of your other Heart disease risk factors, including smoking, High Blood Pressure, and Diabetes
Taking all these steps together may lessen the amount of medicine you need or make the medicine work better-and that reduces your risk for developing heart disease. The following is a description of cholesterol-lowering medicines.
Written and revised by
David Cohen, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.
Explore health topics
More in this topic
Heart & Blood Vessels →
NewsNew Approach to Lowering Cholesterol Tested
A new approach to preventing hardening of the arteries looks promising. California researchers report that they reduced cholesterol levels in mice by honing in on a key group of proteins. Their study appears in the Dec.…
4 December 2004
GuideDoes lowering LDL cholesterol prevent atherosclerosis and heart attacks?
Both heredity and diet have a significant influence on a patient's LDL, HDL and total cholesterol levels. For example, familial hypercholesterolemia (FH) is a common inherited disorder whose victims have a diminished…
4 October 2004
NewsBest GLP-1s for High Cholesterol?: How and Why They Work
GLP-1 medications can improve cholesterol numbers, especially triglycerides, while cutting heart attack and stroke risk. Here’s how they work, which ones show the strongest lipid effects, and why they still need to be paired with proven cholesterol treatments.






