| Table 11-1. Classification and management of blood pressure for adults aged 18 years or older. | ||||||
| Management | ||||||
| Initial Drug Therapy | ||||||
| BP Classification | Systolic BP, mm Hg1 | Diastolic BP, mm Hg1 | Lifestyle Modification | Without Compelling Indication | With Compelling Indications2 | |
Normal | < 120 | and | < 80 | Encourage | ||
Prehypertension | 120-139 | or | 80-89 | Yes | No antihypertensive drug indicated | Drugs for the compelling indications3 |
Stage 1 hypertension | 140-159 | or | 90-99 | Yes | Thiazide-type diuretics for most; may consider ACE inhibitor, ARB, β-blocker, CCB, or combination | Drug(s) for the compelling indications Other antihypertensive drugs (diuretics, ACE inhibitor, ARB, β-blocker, CCB) as needed |
Stage 2 hypertension | ≥ 160 | or | ≥ 100 | Yes | Two-drug combination for most (usually thiazide-type diuretic and ACE inhibitor or ARB or β-blocker or CCB)4 | Drug(s) for the compelling indications Other antihypertensive drugs (diuretics, ACE inhibitor, ARB, β-blocker, CCB) as needed |
1Treatment determined by highest BP category. 2See Table 11-4. 3Treat patients with chronic kidney disease or diabetes to BP goal of < 130/80 mm Hg. 4Initial combined therapy should be used cautiously in those at risk for orthostatic hypotension. ACE = angiotensin-converting enzyme; ARB = angiotensin receptor blocker; BP = blood pressure; CCB = calcium channel blocker. From Chobanian AV et al: The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003;289:2560. | ||||||