Health.am| TABLE 24-47. OBESITY-RELATED SYNDROMES WITH KNOWN MAP LOCATIONS | |||
|
Syndrome |
Candidate Gene |
Chromosomal Locus |
Inheritance |
| Achondroplasia (ACH) | FGFR3 | 4p16.3 | Autosomal dominant |
| Albright hereditary osteodystrophy 2 (AHO2) | None | 15q | Autosomal dominant |
| Albright hereditary osteodystrophy (AHO) | GNAS1 | 20q13.2 | Autosomal dominant |
| Alstrom syndrome | None | 2p13-p12 | Autosomal recessive |
|
Angelman syndrome with obesity | None | 15q11-q13 | Autosomal dominant |
Bardet-Biedl syndrome 1 (BBS1) |
None | 11q13 | Autosomal recessive |
Bardet-Biedl syndrome 2 (BBS2) | None |
16q21 | Autosomal recessive |
Bardet-Biedl syndrome 3 (BBS3) | None | 3p13-p12 |
Autosomal recessive |
Bardet-Biedl syndrome 4 (BBS4) | MYO9A | 15q22.3-23 | Autosomal recessive |
Bardet-Biedl syndrome 5 (BBS5) | None | 2q21 | Autosomal recessive |
Berardinelli-Scip congenital lipodystrophy (BSCL) | None | 9q34 | Autosomal recessive |
Borjeson-Forssman-Lehmann syndrome (BFLS) | FGF13 | Xq26.3 | X-linked |
Carbohydrate-deficient glycoprotein syndrome type 1a (CDGS1A) | PMM2 | 16p13 | Autosomal recessive |
Choroideremia with deafness (CHOD) | None | Xq21.1-21.2 | X-linked |
Cohen syndrome (COH) | None | 8q22-q23 | Autosomal recessive |
|
Familial partial lipodystrophy Dunnigan (FPLD) | Lamin A/C | 1q21-q31 | Autosomal dominant |
Fanconi-Bickel syndrome (FBS) | SLC2A2 | 3q26.1-26.3 | Autosomal recessive |
Insulin resistance syndromes (IRS) | INSR |
19p13.3 | Autosomal dominant |
Mehmo syndrome (MEHMO) | None | Xp22.13-21.1 |
X-linked |
Posterior polymorphous corneal dystrophy (PPCD) | None | 20q11 | Autosomal dominant |
Prader-Willi Syndrome (PWS) | SNRPN | 15q11-q13 | Autosomal dominant |
Simpson-Golabi-Behmel 1 (SGBS1) | GPC3, GPC4 | Xq26 | X-linked |
Simpson-Golabi-Behmel 2 (SGBS2) | None | Xp22 | X-linked |
Thyroid hormone resistance syndrome (THRS) | THRB | 3p24.3 | Autosomal dominant |
Ulnar-mammary syndrome (UMS) or Schinzel syndrome | TBX3 | 12q23-24.1 | Autosomal dominant |
Wilson Turner | None | Xp21.1-q22 | X-linked |
|
SOURCE: Derived from Chagnon YC, Perusse L, Weisnegal SJ, et al. The human obesity gene map: the 1999 update. Obes Res 2000, 8:89-117 | |||