TABLE 3-19. TREATMENT REGIMENS FOR ACUTE PID
| TABLE 3-19. TREATMENT REGIMENS FOR ACUTE PIDa |
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Recommended inpatient regimens Parenteral regimen A Cefotetanb 2 g IV q12h, plus doxycycline, 100 mg IV q12h. Use IV for minimum of 48 hours after patient improves. After discharge, continue doxycycline 100 mg PO BID to complete 14-day course or Parenteral regimen B Clindamycin, 900 mg IV q8h, plus gentamicin 2 mg/kg IV or IM in one loading dose, followed by a maintenance dose of 1.5 mg/kg IV q8h in patients with normal renal function. Use IV for minimum of 48 hours after patient improves. After discharge, continue doxycycline 100 mg PO BID to complete 14 days total; or continue clindamycin 450 mg PO QID to complete 14-day course as an alternative. Recommended outpatient regimens Ceftriaxone, 250 mg IM or Cefoxitin, 2 g IM, plus probenecid 1 g PO or Other third-generation cephalosporin (ceftizoxime or cefotaxime) plus Doxycycline, 100 mg PO BID for 14 days Recommended to have a test of cure evaluation (7-10 days if use culture; 1 month if testing with NAATs) Management of sex partners As in any STD, partners should be evaluated for other STDs and treated empirically for N. gonorrhoeae and C. trachomatis infection |
| a CDC STD Treatment Guidelines, 1998. |
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b Other cephalosporins such as ceftizoxime, cefotaxime, or ceftriaxone provide adequate gonococcal, other facultative gram-negative aerobic, and anaerobic coverage and may also be used in appropriate doses. NAATs = nucleic acid amplification tests. |