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Table 45-7 Efficacy of standard anticonvulsants in bipolar depression in double-blind trials (reporting results of at least eight bipolar subjects)













































Table 45-7 Efficacy of standard anticonvulsants in bipolar depression in double-blind trials (reporting results of at least eight bipolar subjects)
      Improvement, %
Drug Investigator N Responders Nonresponders
Carbamazepine Ballenger and Post 1978 9 44 56
  Post et al. 1984 25

48


52

Lamotrigine

Frye et al. 2000

38

45


55


Calabrese et al. 1999

195




At 200 mg/day


51

49


At 50 mg/day


41

59

Gabapentin

Frye et al. 2000

38

27

73

Note. Case reports and case series that did not include all consecutive patients treated with a novel anticonvulsant were excluded from this table.