| Table 40-4 Summary of Agency for Health Care Planning and Research (AHCPR) meta-analysis of randomized clinical trials of depression-focused psychotherapy as acute-phase treatments of outpatients with major depressive disorder | |||||
|
Type of depression- focused psychotherapy |
Overall efficacy, % (SD) |
Therapy vs. wait list, % (SD) |
Therapy vs. placebo, % (SD) |
Therapy vs. other therapy, % (SD) |
Therapy vs. drug alone, % (SD) |
| Behavior therapy |
55.3 (9.3) [10] |
17.1 (34.0) [5] |
N/A |
9.1 (19.9) [6] |
23.9 (11.6) [2] |
| Cognitive therapy |
46.6 (6.9) | 30.1 (22.0) [2] | 9.4 (8.3) [1] | -4.4 (16.9) [6] | 15.3 (26.1) [3] |
Interpersonal psychotherapy | 52.3 (6.1) [1] | N/A | 22.6 (8.4) [1] |
13.3 (8.6) | 12.3 (8.6) [1] |
Note. Intent-to-treat samples combined studies of adult and geriatric patients. Studies selected on the basis of randomized assignment, use of control conditions, and reporting of categorical response rates. Numbers in parentheses are the standard deviations of the estimated percentage of responders; bracketed numbers are the numbers of study cells on which these estimates are calculated. | |||||
Source. Adapted from Depression Guideline Panel 1993. | |||||