Table 39-7 Clinically important parameters of common antimanic medications
| Table 39-7 Clinically important parameters of common antimanic medications | ||||
|
Drug |
Dosage range (mg/day) |
Plasma level |
Half-life (hours) |
Protein binding (%) |
| Lithium | 600-2,100 | 0.5-1.5 mEq/L | 14-30 | 0 |
| Carbamazepine | 400-1,200 | 4-12 μg/mL | 13-17 | 70-80 |
| Valproic acid | 500-1,500 | 50-100 μg/mL | 6-16 | 95 |
|
Lamotrigine | 50-2,00 | NA | 15-70 | |
Gabapentin | 300-2,400 | NA | 6-7 | |
Topiramate | 500-1,500 | NA | 18-23 | |