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TABLE 418-5 -NUCLEOSIDE COMBINATIONS THAT ARE GENERALLY NOT RECOMMENDED

REGIMEN REASON FOR NOT USING
Stavudine plus zidovudine Antagonistic intracellular phosphorylation
Zalcitabine plus didanosine Overlapping toxicity (neuropathy)
Zalcitabine plus stavudine Overlapping toxicity (neuropathy)
Zalcitabine plus lamivudine Little data; potential for cross-resistance