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TABLE 418-1 -NAMES AND USUAL ADULT ORAL DOSES OF ANTI-HIV DRUGS













































DRUG DOSAGE
Nucleoside Reverse Transcriptase Inhibitors
Zidovudine (AZT) 200 mg three times daily or 300 mg twice daily *
Didanosine (ddI) >60 kg: 200 mg twice daily (tablets) between meals

< 60 kg: 125 mg twice daily (tablets) between meals

Zalcitabine (ddC)0.75 mg three times daily
Stavudine (d4T)>60 kg: 40 mg twice daily

<60 mg: 30 mg twice daily

Lamivudine (3TC)>50 kg: 150 mg twice daily *

<50 kg: 2 mg/kg twice daily

Abacavir300 mg twice daily
Non-Nucleoside Reverse Transcriptase Inhibitors
Nevirapine200 mg/d for 14 days, then 200 mg twice daily
Delavirdine400 mg three times daily (in water as slurry)
Efavirenz600 mg once daily at nighttime
Protease Inhibitors
Indinavir800 mg q8h between meals or with low-fat meal
Ritonavir600 mg q12h with food if possible
Saquinavir 
  Hard-gel capsule600 mg three times daily with large meal
  Soft-gel capsule1200 mg three times daily with large meal
Nelfinavir750 mg three times daily with food or light snack

* Zudovudine is also available in a combined capsule with lamivudine.

For the buffered powder formulation of didanosine, the doses are 250 mg twice daily for patients >60 kg and 167 mg twice daily for patients <60 kg.