TABLE 413-1 -ESOPHAGEAL COMPLICATIONS OF HIV INFECTION

AGENT	FREQUENCY*(% )	CD4 COUNT (mm3 )	CLINICAL FEATURES	DIAGNOSIS	TREATMENT
Candida	50-70	<200	Odynophagia, thrush, diffuse pain, usually afebrile	Usually treated empirically. Endoscopy shows plaque	Fluconazole
Cytomegalovirus (CMV)	10-20	<50	Odynophagia, focal pain, usually febrile	Biopsy of ulcer to show CMV inclusions	Ganciclovir
Herpes simplex virus (HSV)	2-5	<200	Odynophagia, oral HSV lesions common, usually afebrile	Biopsy of ulcer to show HSV inclusions	Acyclovir
Idiopathic	10-20	<300	Odynophagia, focal pain, usually afebrile	Negative biopsy of ulcer	Prednisone or thalidomide

Approximate frequency in HIV-infected patients with odynophagia