TABLE 411-3 -COMPARATIVE CLINICAL AND RADIOLOGIC FEATURES OF CEREBRAL TOXOPLASMOSIS, PRIMARY CNS LYMPHOMA, AND PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY

	CLINICAL ONSET			NEURORADIOLOGIC FEATURES
	Temporal Profile	Level of Alertness	Fever	Number of Lesions	Type of Lesions	Location of Lesions
Cerebral toxoplasmosis	Days	Reduced	Common	Multiple	Spherical, ring-enhancing	Basal ganglia, cortex
Primary CNS lymphoma	Days to weeks	Variable	Absent	One or few	Irregular, weakly enhancing	Periventricular white matter
Progressive multifocal leukoencephalopathy	Weeks	Preserved	Absent	Multiple	Nonenhancing, no mass effect	White matter