TABLE 411-2 -NEUROANATOMIC CLASSIFICATION OF THE LATE COMPLICATIONS OF HIV-1 INFECTION

Meningitis and headache

Diffuse brain diseases

With preservation of consciousness
- AIDS dementia complex
With concomitant depression of arousal
- Metabolic encephalopathies (alone or as an exacerbating influence)
- Toxoplasmosis ("encephalitic" form)
- Cytomegalovirus encephalitis
- Herpes encephalitis

Focal brain diseases

Myelopathies

Subacute/chronic, progressive and "diffuse"
- Vacuolar myelopathy
- HTLV-1-associated myelopathy
Acute/subacute and segmental
- Transverse myelitis
  - Varicella-zoster virus (herpes zoster)
  - Spinal epidural or intradural lymphoma
- With polyradiculopathy
  - Cytomegalovirus

Peripheral neuropathies

Polyneuropathies
- HIV-1-related distal sensory polyneuropathy
- Nucleoside toxic neuropathies
- Autonomic neuropathy
- CD8 cell neuropathy associated with diffuse infiltrative lymphocytosis syndrome
Focal neuropathies and radiculopathies
- CMV polyradiculopathy
- Mononeuritis multiplex
  - CMV-related malignant type
  - Early, benign vasculopathic form
- Mononeuropathy associated with aseptic meningitis
- Neuropathy related to lymphomatous meningitis or epidural compression

Myopathies