| Endocarditis prophylaxis recommended2 | Endocarditis prophylaxis not recommended |
| 1. Dental Dental extractions Periodontal procedures Dental implant placement or reimplantation Endodontic (root canal) instrumentation or surgery only beyond the apex Subgingival placement of antibiotic fibers or strips Initial placement of orthodontic bands but not brackets Postoperative suture removal Intraligamentary local anesthetic injections Prophylactic cleaning of teeth or implants where bleeding is anticipated Orthodontic appliance adjustment | 1. Dental
Restorative dentistry (filling cavities, operative and prosthodontic) with or without retraction cord4 Local anesthetic injections (nonintraligamentary) Intracanal endodontic treatment; post placement and buildup Placement of rubber dams, removable prosthodontic, or orthodontic appliances Taking of oral impression Fluoride treatments |
| 2. Respiratory tract Tonsillectomy, adenoidectomy Surgical operations that involve intestinal or respiratory mucosa Bronchoscopy with a rigid bronchoscope |
2. Respiratory tract Endotracheal intubation Bronchoscopy with a flexible bronchoscope, with or without biopsy5 Tympanostomy (insertion) |
| 3. Gastrointestinal tract3 Sclerotherapy for esophageal varices Esophageal stricture dilation Endoscopic retrograde cholangiography with biliary obstruction Vaginal hysterectomy5 Biliary tract surgery Surgical operations that involve intestinal mucosa |
Gastrointestinal tract Transesophageal echocardiography5 Endoscopy with or without gastrointestinal biopsy5 |
| 4. Genitourinary tract Prostatic surgery Cystoscopy Urethral dilation |
4. Genitourinary tract Vaginal delivery5 Cesarean section In the absence of infection: urethral catheterization, uterine dilation and curettage, therapeutic abortion, sterilization procedures, insertion or removal of intrauterine devices |
| 5. Other Cardiac catheterization, including balloon angioplasty; implanting cardiac pacemakers or defibrillators and coronary stents; incision or biopsy of surgically scrubbed skin; circumcision |
Reproduced, with permission, from Dajani AS et al: Prevention of bacterial endocarditis. Recommendation by the American Heart Association. JAMA 1997;277:1794. Copyright © 1997 by American Medical Association.
1This table lists selected procedures but is not meant to be all-inclusive.
2Recommended for individuals with high- and moderate-risk cardiac conditions
3Prophylaxis is recommended for high-risk patients, optional for moderate-risk patients.
4Clinical judgment may indicate antibiotic use in selected circumstances that may create significant bleeding.
5Prophylaxis is optional for high-risk patients.