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BOX 98-1. American Joint Committee on Cancer TNM classification for squamous cell cancer of the oral cavity (1993) |
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Definition of TNM |
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Primary tumor (T) |
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Tx Primary tumor cannot be assessed |
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T0 No evidence of primary tumor |
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Tis Carcinoma in situ |
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T1 Tumor 2 cm or less in greater dimension |
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T2 Tumor more than 2 cm but not more than 4 cm in greater dimension |
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T3 Tumor more than 4 cm in greatest dimension |
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T4 (lip) Tumor invades adjacent structures (e.g., through cortical bone, tongue, skin of neck) |
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Regional lymph nodes (N) |
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Nx Regional lymph nodes cannot be assessed |
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N0 No regional lymph node metastasis |
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N1 Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension |
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N2 Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension; or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension; or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension |
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N2a Metastasis in single ipsilateral lymph node more than 3 cm but not more than 6 cm in greatest dimension |
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N2b Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension |
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N2c Metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension |
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N3 Metastasis in a lymph node more than 6 cm in greatest dimension |
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Distant metastasis (M) |
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Mx Presence of distant metastasis cannot be assessed |
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M0 No distant metastasis |
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M1 Distant metastasis |
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