TABLE 90-4
| Table 90-4. Representative Local Control Rates and Survival for Patients with Squamous Cell Carcinoma of Common Head and Neck Sites Treated with Definitive Radiotherapy | ||
| Stage by site | Local control (%) | Survival* (%) |
Oral cavity |
||
Oral tongue |
||
T1 |
80-90 |
75-80 |
T2 |
60-85 |
40-60 |
T3 |
30-50 |
20-30 |
T4 |
24-45 |
10-15 |
Floor of mouth |
||
T1 |
75-85 |
70-85 |
T2 |
60-80 |
50-60 |
T3 |
30-50 |
15-40 |
T4 |
5-30 |
5-20 |
Oropharynx |
||
Base of tongue |
||
T1 |
80-95 |
65-85 |
T2 |
60-75 |
40-55 |
T3 |
40-65 |
15-20 |
T4 |
30-50 |
5-20 |
Tonsil/tonsillar fossa |
||
T1 |
75-95 |
65-85 |
T2 |
60-80 |
55-60 |
T3 |
35-70 |
20-40 |
T4 |
20-30 |
10-15 |
Soft palate |
||
T1 |
90-100 |
90-95 |
T2 |
75-85 |
65-75 |
T3 |
60-70 |
30-40 |
T4 |
25-35 |
10-15 |
Nasopharynx |
||
T1 |
70-85 |
60-75 |
T2 |
50-60 |
50-65 |
T3 |
20-45 |
25-50 |
T4 |
15-35 |
5-30 |
Hypopharynx |
||
Pyriform sinus |
||
T1 |
60-70 |
30-50 |
T2 |
40-50 |
20-45 |
T3 |
30-40 |
15-25 |
T4 |
10-25 |
5-20 |
Larynx |
||
Supraglottic |
||
T1 |
80-90 |
65-90 |
T2 |
60-80 |
50-65 |
T3 |
35-70 |
35-55 |
T4 |
30-60 |
15-40 |
Glottis |
||
T1 |
85-95 |
80-95 |
T2 |
65-75 |
60-85 |
T3 |
20-35 |
35-60 |
T4 |
15-30 |
10-30 |
| Local control is for radiation alone. Survival data include surgical salvage for radiation failures. Overlap in the two sets of figures is due to data coming from different patient series, which are a heterogeneous mix of nodal stages, Kmofsky scores, tumor differentiation. | ||
| *Adapted from Laramore.157 | ||