TABLE 74-2 Definition of TNM-Nasopharynx

TABLE 74-2  Definition of TNM-Nasopharynx

TX

Cannot be assessed

Stage 0

Tis

N0

M0

T0

No evidence

Stage I

T1

N0

M0

Tis

Carcinoma in situ

Stage IIA

T2a

N0

M0

T1

Tumor confined to the nasopharynx

Stage IIB

T1

N1

M0

T2

Tumor extends to soft tissues

T2

N1

M0

T2a Tumor extends to the oropharynx and/or nasal cavity w/o parapharyngeal extension

T2a

N1

M0

T2b Any tumor with parapharyngeal extension

T2b

N1

M0

T3

Tumor involves bony structures and/or paranasal sinuses

T2b

N1

M0

T4

Tumor with intracranial extension and/or involvement of cranial nerves, infratemporal fossa, hypopharynx, orbit, or masticator space

Stage III

T1 T2a

N2 N2

M0 M0

Regional Lymph Nodes (N)

T2b

N2

M0

  The distribution and the prognostic impact of regional lymph node spread from nasopharynx cancer, particularly of the undifferentiated type, are different from those of other head and neck mucosal cancers and justify the use of a different N classification scheme.

T3

N0

M0

NX Regional lymph nodes cannot be assessed

T3

N1

M0

N0 No regional lymph node metastasis

T3

N2

M0

N1 Unilateral metastasis in lymph node(s), ≤6 cm in greatest dimension, above the supraclavicular fossa

T4

N0

M0

N2 Bilateral metastasis in lymph node(s), ≤6 cm in greatest dimension, above the supraclavicular fossa

T4

N1

M0

N3 Metastasis in lymph node(s), >6 cm and/or to supraclavicular fossa

T4

N2

M0

N3a Greater than 6 cm in dimension

Any T

N3

M0

N3b Extension to the supraclavicular fossa

Any T

Any N

M1