TABLE 241-8. WHO SCORING SYSTEM FOR GESTATIONAL TROPHOBLASTIC DISEASE
| TABLE 241-8. WHO SCORING SYSTEM FOR GESTATIONAL TROPHOBLASTIC DISEASE | ||
| Factor | Description | Scorea |
| Age (yr) |
≤ 39 > 39 |
0 1 |
| Prior pregnancy |
Hydatidiform mole Abortion Term |
0 1 2 |
| Interval between prior pregnancy and start of chemotherapy (mo) |
< 4 4-6 7-12 > 12 |
0 1 2 4 |
| β-hCG (IU/L) |
> 1000 1,000 - > 10,000 10,000 - 100,000 > 100,000 |
0 1 2 4 |
| ABO blood group |
OxA or AxOb B or ABc |
1 2 |
| Size of largest tumor (cm) |
3-5 > 5 |
1 2 |
| Site of metastases |
Spleen, kidney GI tract, liver Brain |
1 2 4 |
| Number of metastases |
1-3 4-8 > 8 |
1 2 4 |
| Prior chemotherapy |
Single drug ≥ 2 drugs |
2 4 |
| aTotal score: 0-4 = low risk; 5-7 = intermediate risk; ≥ 8 = high risk. | ||
| bCombination of maternal and paternal blood type. | ||
| cMaternal blood type. | ||
| WHO = World Health Organization; β-hCG = β subunit of human chorionic gonadotropin. | ||