Table 17.4. Prognostic Factors in Node-Negative Breast Cancer
| Table 17-4. Prognostic Factors in Node-Negative Breast Cancer. | ||
| Prognostic Factor | Increased Recurrence | Decreased Recurrence |
| Size | T3, T2 | T1, T0 |
| Hormone receptors | Negative | Positive |
| DNA flow cytometry | Aneuploid | Diploid |
| Histologic grade | High | Low |
| Tumor labeling index | < 3% | > 3% |
| S phase fraction | > 5% | < 5% |
| Lymphatic or vascular invasion | Present | Absent |
| Cathepsin D | High | Low |
| HER-2/neu oncogene | High | Low |
| Epidermal growth factor receptor | High | Low |