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Table 118-1. Oncogenes in Epithelial Ovarian Cancer

Table 118-1. Oncogenes in Epithelial Ovarian Cancer
Receptor Kinases
Overexpression of HER2
Continued expression of EGFR
Novel expression of FMS
Non-receptor kinases
Amplification of PI3 kinase
Amplification of AKT kinase
SRC kinase activated physiologically
Ras rarely mutated but frequently activated physiologically
Overexpression of MYC
Activation of STAT3
Adapted from Bast RC Jr, Mills GB.75