TABLE 13-2 - Drugs Used as Mood Stabilizers
| Drugs | Starting Dosage | |
| Drug | Side-Effect Profile | |
| Lithium | Therapeutic levels | |
| CNS: Endocrine: Cardiac: Renal: Dermatologic: GI: Hematologic: Other: |
sedation, cognitive clouding, fine tremor abnormal TSH, clinical hypothyroidism T-wave change, sinus arrhythmia polyuria acne, psoriasis nausea, vomiting, diarrhea benign leukocytosis weight gain, fluid retention | |
| Toxic levels CNS: Cardiac: |
ataxia, coarse tremor, confusion, seizure, coma, death sinus arrest | |
| Valproate | Therapeutic levels CNS: Endocrine: Dermatologic: Hepatic: GI: Hematologic: Other: Toxic levels CNS: Cardiac: Idiosyncratic Hepatic: GI: Hematologic: |
somnolence, ataxia, tremor menstrual irregularities, thyroid abnormalities alopecia, rash mild transaminitis nausea, vomiting, indigestion thrombocytopenia, platelet dysfunction edema ataxia, confusion, coma, death cardiac arrest fatal hepatotoxicity pancreatitis ag ranulocytosis |
| Carbamazepine | Therapeutic levels CNS: Dermatologic: Cardiac: Hematologic: GI: Toxic levels CNS: Cardiac: Respiratory: Idiosyncratic Hematologic: |
ataxia, sedation, dizziness, diplopia rash decreased atrioventricular conduction benign leukopenia nausea somnolence, autonomic instability, coma atrioventricular block respiratory depression agranulocytosis, pancytopenia, aplastic anemia |