Effective
- Major depression (unipolar)
- Bipolar depression
- Prophylaxis against recurrence of major depression (unipolar)
- Panic disorder
- Social phobia
- Depression with psychotic features in combination with antipsychotic
- Bulimia
- Neuropathic pain (tricyclic drugs)
- Enuresis (imipramine best studied)
- Obsessive-compulsive disorder (clomipramine and SSRls)
- Atypical depression (SSRls or monoamine oxidase inhibitors)
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Probably effective
- Attention-deficit/hyperactivity disorder
- Cataplexy due to narcolepsy
- Dysthymia (chronic depression)
- Generalized anxiety disorder
- Organic mood disorders
- Posttraumatic stress disorder
- Pseudobulbar affect (pathological laughing or crying)
Possibly effective
- School phobia and separation anxiety
- Personality disorders
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Reproduced by permission from Hyman SE, Arana GW, Rosenbaum JE Handbook of psychiatric drug therapy. 4th ed. Philadelphia: Lippincott Williams and Wilkins, 2000.
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