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TABLE 12-1 - Commonly Prescribed Antidepressants

Drug (Brand Name) Suggested Starting Dosage * Suggested Maximum Dosage *
SSRls
Fluoxetine (Prozac) 5-20 mg/day 80 mg/day
Sertraline (Zoloft) 25-50 mg/day 200 mg/day
Paroxetine (Paxil) 10-20 mg/day 50 mg/day
Fluvoxamine (Luvox) 25-50 mg qhs 300 mg qhs
Citalopram (Celexa) 20 mg/day 60 mg/day
Escitalopram (Lexapro) 10 mg/day 40 mg/day
TCAs
Nortriptyline (pamelor) 10-25 mg/day 150 mg/day
Imipramine (Tofranil) 10-50 mg/day 300 mg/day
Desipramine (Norpramin) 10-25 mg/day 300 mg/day
Clomipramine (Anafranil) 25-50 mg/day 250 mg/day
MAOls
Tranylcypromine (Parnate) 10-20 mg/day 60 mg/day
Phenelzine (Nardil) 15-30 mg/day 90 mg/day
Other antidepressants
Bupropion (Wellbutrin) 75-100 mg/day 150mg tid
Bupropion SR (Wellbutrin SR. Zyban) 150 mg/day 200 mg bid
Nefazodone (Serzone) 50-100 mg bid 600 mg/day
Venlafaxine (Effexor) 25 mg tid 125 mg tid
Mirtazapine (Remeron) 15mg qhs 45 mg qhs
Trazodone (Desyrel) 50 mg qhs 400 mg qhs

* Geriatric patients generally require lower doses.
Modified from Stoll A, Psychopharmacology reference card 1.1996.