Peripheral Vascular Disease
Key points
- In peripheral vascular disease, not enough blood flows to the legs.
- The most common symptom of peripheral vascular disease is pain or cramping in the legs or buttocks that starts when you exercise and goes away when you rest.
- Your doctor will review your personal risk factors for atherosclerosis and your family history.
- Once you have peripheral vascular disease, your arteries usually will remain narrowed.
What Is It?
In peripheral vascular disease, not enough blood flows to the legs. It usually is caused by fatty deposits (called plaques) that build up along the walls of blood vessels. This buildup shrinks the size of the passageway and reduces the amount of blood that can flow through. Doctors call this atherosclerosis. The most common symptom is intermittent claudication, a cramping in the legs or buttocks when you exercise that goes away when you rest. The risk factors for getting peripheral vascular disease are the same as the risk factors for coronary heart disease, and include:
- Smoking cigarettes or using other forms of tobacco (such as snuff and chew)
- An abnormally high level of cholesterol (hypercholesterolemia)
- An abnormally low level of high-density lipoprotein (HDL, the good cholesterol)
- High blood pressure (hypertension)
- Diabetes
- Family history of coronary artery disease
- Obesity
- Physical inactivity (too little regular exercise)
Symptoms
The most common symptom of peripheral vascular disease is pain or cramping in the legs or buttocks that starts when you exercise and goes away when you rest. Often the pain is described as a deep ache, especially in the calf muscle. The pain may extend to the foot or up toward the thigh and buttock. Sometimes there is just numbness in the leg, or a sense that one leg gets tired when you walk. A foot or toes also may feel cold or numb.
If the arteries are severely narrowed, you could experience leg pain when you are not exercising. If blood flow stops completely (usually because a blood clot forms in the narrowed vessel), parts of the leg may become pale or turn blue, feel stone cold to the touch and eventually develop gangrene.
Diagnosis
Your doctor will review your personal risk factors for atherosclerosis and your family history. Your doctor will ask if you or any family members have heart disease, high cholesterol, diabetes, high blood pressure, or any other circulation disorder. During the physical examination, your doctor will feel the pulse in your upper leg (near the groin), on the inside of your ankle, the top of your foot and the back of your knee. Any weakness in a pulse may be a sign of narrowed arteries.
Usually the doctor can diagnose peripheral vascular disease based upon your symptoms, risk factors, the examination of your legs, and the strength of your pulses. If more information is needed, other tests include blood pressure measurements taken at various locations in the legs, Doppler studies of blood flow, special ultrasound testing, and exercise testing on a treadmill. If your doctor suspects that you may need a procedure to help open a blocked blood vessel, you may need a magnetic resonance imaging (MRI) scan of your arteries or an angiogram, which is an X-ray test that uses dye in the narrowed arteries to reveal the pattern of blood flow and spot blockages.
Written and revised by
Gerald Hurowitz, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
health.am provides general information, not medical advice. Always consult a qualified health professional about your own health.