Hageman factor deficiency
Key points
- This is an inherited disorder that causes prolonged clotting (coagulation) of blood in a test tube without a clinical bleeding tendency, and results from a deficiency of the plasma protein factor XII.
- Factor XII deficiency is a hrare ereditary disorder that is usually found when clotting tests are done for routine screening.
- This condition is usually discovered by the health care provider when prolonged clotting is noticed in the process of running other laboratory tests.
Definition
This is an inherited disorder that causes prolonged clotting (coagulation) of blood in a test tube without a clinical bleeding tendency, and results from a deficiency of the plasma protein factor XII.
Causes, incidence, and risk factors
Factor XII deficiency is a hrare ereditary disorder that is usually found when clotting tests are done for routine screening. It is not associated with abnormal bleeding.
Symptoms
There are usually no symptoms.
Signs and tests
- Prolonged partial thromboplastin time
- Abnormal factor XII assay
Treatment
Treatment is generally unnecessary.
Expectations (prognosis)
The outcome is expected to be good without treatment.
Complications
There are usually no complications.
Calling your health care provider
This condition is usually discovered by the health care provider when prolonged clotting is noticed in the process of running other laboratory tests.
Prevention
This is an inherited disorder. There is no known way to prevent it.
Frequently asked questions
What is hageman factor deficiency?
This is an inherited disorder that causes prolonged clotting (coagulation) of blood in a test tube without a clinical bleeding tendency, and results from a deficiency of the plasma protein factor XII.
What are the risk factors for hageman factor deficiency?
Factor XII deficiency is a hrare ereditary disorder that is usually found when clotting tests are done for routine screening. It is not associated with abnormal bleeding.
What are the symptoms of hageman factor deficiency?
- Prolonged partial thromboplastin time
- Abnormal factor XII assay Treatment Treatment is generally unnecessary.
Can hageman factor deficiency be prevented?
This is an inherited disorder. There is no known way to prevent it.
Written and revised by
David Cohen, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
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