East African Trypanosomiasis
Key points
- There are two types of African trypanosomiasis (also called sleeping sickness); each is named for the region of Africa in which they are found.
- An individual will get East African trypanosomiasis if they are bitten by a tsetse fly infected with the Trypanosoma brucei rhodesiense parasite.
- If a person fails to receive medical treatment for East African trypanosomiasis, death will occur within several weeks to months.
- East African trypanosomiasis is found in parts of Eastern and Central Africa, including Uganda, Kenya, Tanzania, Malawi, Ethiopia, Zaire, Zimbabwe, and Botswana.
East African TrypanosomiasisWhat is African trypanosomiasis?
There are two types of African trypanosomiasis (also called sleeping sickness); each is named for the region of Africa in which they are found. The disease is caused by a parasite named Trypanosoma brucei rhodesiense (tri-PAN-o-SO-ma BREW-see-eye rho-DEE-see-ense), carried by the tsetse fly. Worldwide, approximately 40,000 new cases of both East and West African trypanosomiasis are reported to the World Health Organization each year. However, the majority of cases are not reported due to a lack of infrastructure and it is likely that there are more than 100,000 new cases annually. Since 1967, twenty-one cases of East African trypanosomiasis have been reported within the United States, all among individuals who had traveled to Africa. (See also West African trypanosomiasis.)
How is East African trypanosomiasis spread?
An individual will get East African trypanosomiasis if they are bitten by a tsetse fly infected with the Trypanosoma brucei rhodesiense parasite. The tsetse fly is common only to Africa.
Is East African trypanosomiasis a serious illness?
Yes. If a person fails to receive medical treatment for East African trypanosomiasis, death will occur within several weeks to months.
Where can you become infected with East African trypanosomiasis?
East African trypanosomiasis is found in parts of Eastern and Central Africa, including Uganda, Kenya, Tanzania, Malawi, Ethiopia, Zaire, Zimbabwe, and Botswana. Areas where infection is spread are largely determined by the location of the infected tsetse fly and wild animal population.
What are the symptoms of East African trypanosomiasis?
A bite by the tsetse fly is often painful and can develop into a red sore, also called a chancre (SHAN-ker). Fever, severe headaches, irritability, extreme fatigue, swollen lymph nodes, and aching muscles and joints are common symptoms of sleeping sickness. Some people develop a skin rash. Progressive confusion, personality changes, slurred speech, seizures, and difficulty in walking and talking occur when infection has invaded the central nervous system. If left untreated, infection becomes worse and death will occur within several weeks or months.
How soon after infection will I have symptoms of East African trypanosomiasis?
Symptoms begin within 1 to 4 weeks of getting an infected tsetse fly bite.
Written and revised by
Gerald Hurowitz, M.D.
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