Cervical Cancer
Key points
- The cervix is a small, donut-shaped structure, located at the top of the vagina.
- In its early stages, cervical cancer does not cause any symptoms.
- The diagnosis of cervical cancer usually begins with a pelvic exam.
- Cervical cancer is a slower growing cancer and can take years to invade nearby tissues.
What Is It?
The cervix is a small, donut-shaped structure, located at the top of the vagina. It is the entrance to the uterus. Cervical cancer begins with abnormal, microscopic changes in cells in the outer layer of the cervix, called the epithelium. This stage is called dysplasia. If changes continue to occur, cells may become cancerous and grow out of control.
Cervical cancer tends to grow slowly. It may remain in an early stage, confined to the cervical covering, for two to 10 years. Once cancer moves beyond this layer, however, it invades nearby tissue, including the main body of the uterus, the vagina, bladder and rectum.
The cause of cervical cancer is unknown, but infection with certain types of human papilloma virus (HPV) significantly increases a woman's risk of developing cervical cancer. Cigarette smoking also may contribute to cervical cancer.
Symptoms
In its early stages, cervical cancer does not cause any symptoms. Once it begins to spread, it may cause a blood-tinged or discolored vaginal discharge that does not itch, spotting after intercourse, or abnormal bleeding. These symptoms, however, aren't unique to cervical cancer and may occur with many disorders of the female reproductive tract.
More advanced stages of cervical cancer can cause pelvic pain, appetite loss, weight loss and anemia.
Diagnosis
The diagnosis of cervical cancer usually begins with a pelvic exam. The doctor uses a speculum, an instrument that holds the walls of the vagina open to make it easier to inspect your cervix and vagina, and do a Pap test. The Pap test is a quick, painless procedure in which the doctor gently brushes the surface lining and the canal of your cervix to obtain a sample of mucus and cells. The cells are then sent to a laboratory for examination. If the Pap test indicates dysplasia (irregularly shaped cells) or possibly cancerous cells, a gynecologist will examine your cervix and vagina with a special instrument called acolposcope and will do a biopsy to further examine the abnormal cells. A colposcope contains a magnifying lens that makes the cervix appear larger. In a biopsy, a small piece of tissue is removed from the cervix so it can be examined in a laboratory. A vinegar solution is applied to the cervix and vagina so that abnormal areas turn white temporarily. This helps the gynecologist determine where to remove tissue for the biopsy.
Another test called endocervical curettage or endocervical scraping also may be done. A thin instrument is used to take a scraping of the cells inside the inner opening of the cervix. These are cells that may be hidden from view during colposcopy. A local anesthetic is used to numb the cervix during this and other types of biopsies.
Written and revised by
Gerald Hurowitz, M.D.
Our doctors write and review articles for accuracy and keep them up to date.
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