The significance of the site of recurrence to subsequent breast cancer survival

Key points
- The study was a review of 294 patients from a breast cancer database, who were treated for operable breast cancer and subsequently developed a recurrence between 1989 and 2003.
- Bates The Breast Unit, William Harvey Hospital, Ashford, Kent TN24 0LZ, UK Accepted 6 September 2006.
- Patients were divided into four groups according to the site of first recurrence (local, lymph node, bone or visceral).
- Breast Cancer Specific Survival (BCSS) was compared using Kaplan–Meier life table analysis and the log rank test.
The 3-year survival of patients with recurrent breast cancer was determined; the prognosis was progressively worse with local, regional, bone, and visceral metastases
The study was a review of 294 patients from a breast cancer database, who were treated for operable breast cancer and subsequently developed a recurrence between 1989 and 2003. Patients were divided into four groups according to the site of first recurrence (local, lymph node, bone or visceral). Breast Cancer Specific Survival (BCSS) was compared using Kaplan–Meier life table analysis and the log rank test.
Methodology
* A retrospective review was conducted involving 294 patients with recurrent breast cancer between 1989 and 2003
* Breast cancer recurrences were categorized as local, regional, bone, and visceral metastases
Results
* Three-year breast cancer specific survivals were 83% for local recurrence as compared with 33% for lymph node, 23% for bone, and 13% for visceral recurrences
A. Imkampe S. Bendall and T. Bates
The Breast Unit, William Harvey Hospital, Ashford, Kent TN24 0LZ, UK
Accepted 6 September 2006. Available online 16 October 2006.
ScienceDirect
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Written and revised by
Gerald Hurowitz, M.D.
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