Exercise may reduce the risk of epilepsy later in life for men
Key points
- New research suggests that men who exercise vigorously as young adults may reduce their risk of developing epilepsy later in life.
- "There are a host of ways exercise has been shown to benefit the brain and reduce the risk of brain diseases," said study author Elinor Ben-Menachem, PhD, MD, with the University of Gothenburg in Sweden and an associate member of the American Academy of Neurology.
- For the study, 1.17 million Swedish men were given cycle tests that measured cardiovascular fitness when they enlisted for mandatory military service at age 18.
- The study found that men who had a high level of fitness were 79 percent less likely to develop epilepsy than those with low fitness levels and 36 percent less likely to develop epilepsy than those with medium fitness levels.
New research suggests that men who exercise vigorously as young adults may reduce their risk of developing epilepsy later in life. The study is published in the September 4, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. Epilepsy is a brain disease that causes repeated seizures over time.
"There are a host of ways exercise has been shown to benefit the brain and reduce the risk of brain diseases," said study author Elinor Ben-Menachem, PhD, MD, with the University of Gothenburg in Sweden and an associate member of the American Academy of Neurology. "This is the first study in humans to show that exercise may also reduce the risk of epilepsy, which can be disabling and life-threatening."
For the study, 1.17 million Swedish men were given cycle tests that measured cardiovascular fitness when they enlisted for mandatory military service at age 18. The participants were then assessed for epilepsy for an average of 25 years. During follow-up, 6,796 men were diagnosed with epilepsy.
The study found that men who had a high level of fitness were 79 percent less likely to develop epilepsy than those with low fitness levels and 36 percent less likely to develop epilepsy than those with medium fitness levels.
The proportion of men with high fitness who developed epilepsy in the study was 0.48% (2,381 out of 496,973 with high fitness). The proportion of men with medium fitness who developed epilepsy was 0.62 percent (3,913 out of 629,876 with medium fitness). The proportion of men with low fitness who developed epilepsy was 1.09 percent (502 out of 46,230 with low fitness).
The results were lessened only slightly after considering genetic factors and a prior history of traumatic brain injury, stroke or diabetes.
Epilepsy is the third most common neurological disorder in the United States after Alzheimer’s disease and stroke.It is equal in prevalence to cerebral palsy, multiple sclerosis and Parkinson’s disease combined.Brain Scan MRI
Epilepsy is not a single entity but a family of more than 40 syndromes that affect nearly 3 million people in the U. S.and 50,000,000 worldwide.
Epilepsy strikes most often among the very young and the very old, although anyone can get it at any age. In the U.S., it currently affects more than 326,000 children under age fifteen and more than 90,000 of them have severe seizures that cannot be adequately treated.
The number of cases in the elderly is beginning to soar as the baby boom generation approaches retirement age. Currently more than 570,000 adults aged 65 and above in the U.S. have the condition.
Epilepsy imposes an annual economic burden of $15.5 billion on the nation in associated health care costs and losses in employment, wages, and productivity.
The mortality rate among people with epilepsy is two to three times higher than the general population and the risk of sudden death is 24 times greater.
Written and revised by
David Cohen, M.D.
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