Viagra useful for ED in men with MS

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Erectile dysfunction (ED) is a common problem for men with multiple sclerosis and now new research indicates that Viagra (sildenafil) is an effective and well-tolerated treatment for erectile difficulties in such patients.

In the study, 217 relatively young men were randomly assigned to Viagra or placebo for 12 weeks. The study was funded by Pfizer, Inc., which markets the drug Viagra.

“Viagra significantly improved erectile function and the ability to engage in satisfactory sexual activity in ED due to MS,” Dr. Clare J. Fowler, from The National Hospital for Neurology and Neurosurgery, in London, and colleagues report.

Compared with placebo, Viagra was associated with a significant improvement in standard erection scores. Altogether, 89 percent of Viagra-treated patients reported improved erections compared with just 24 percent of those given a placebo.

The randomized phase of the study was followed by a 48-week extension phase in which 180 men were treated with Viagra. At the end of this phase, 95 percent of patients reported improved erections.

Treatment with Viagra also significantly improved quality of life of the men in the study.

Viagra was well tolerated, according to the team. No serious drug-related side effects were seen.

The findings appear in the Journal of Neurology, Neurosurgery, and Psychiatry this month.

SOURCE: Journal of Neurology, Neurosurgery, and Psychiatry May 2005.

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